STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APX24555.1PFAM: NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (290 aa)    
Predicted Functional Partners:
APX24556.1
PFAM: Enoyl-CoA hydratase/isomerase.
  
 0.988
APX24561.1
Methylmalonate-semialdehyde dehydrogenase (acylating); PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
 
 
 0.955
APX21499.1
Biotin carboxyl carrier protein; 'PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme'; 'TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit'; biotin carboxylase.
  
 
 0.834
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.817
APX23966.1
propionyl-CoA synthetase; PFAM: AMP-binding enzyme; Acetyl-coenzyme A synthetase N-terminus; AMP-binding enzyme C-terminal domain.
  
 
  0.817
APX24980.1
acetyl-CoA synthetase; PFAM: AMP-binding enzyme; Acetyl-coenzyme A synthetase N-terminus; AMP-binding enzyme C-terminal domain; TIGRFAM: acetoacetyl-CoA synthase.
  
 
  0.817
acsA-2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.817
APX25593.1
acetyl-CoA synthetase; PFAM: AMP-binding enzyme; AMP-binding enzyme C-terminal domain.
  
 
  0.817
APX21506.1
propionyl-CoA carboxylase carboxyltransferase subunit; PFAM: Carboxyl transferase domain.
  
 
  0.811
APX24671.1
acyl-CoA synthetase (NDP forming); PFAM: CoA binding domain; ATP-grasp domain; Succinyl-CoA ligase like flavodoxin domain.
    
  0.807
Your Current Organism:
Salipiger profundus
NCBI taxonomy Id: 1229727
Other names: CGMCC 1.12377, DSM 27508 [[Salipiger nanhaiensis]], Donghicola sp. ZH114, JCM 19383 [[Salipiger nanhaiensis]], KCTC 32468 [[Salipiger nanhaiensis]], LMG 27365, LMG:27365, S. profundus, Salipiger nanhaiensis, Salipiger nanhaiensis Dai et al. 2015, Salipiger sp. JLT2016, Thiobacimonas profunda, Thiobacimonas profunda Li et al. 2015 emend. Huang et al. 2017, strain JLT2016, strain ZH114 [[Salipiger nanhaiensis]]
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