STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsH-3Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (610 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.874
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.785
APX25459.1
ATP-dependent Clp protease ATP-binding subunit ClpC; 'PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain, pathogenicity island component; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA)'; Belongs to the ClpA/ClpB family.
 
  
 0.785
APX25461.1
Heat shock protein HtpX; PFAM: Peptidase family M48.
 
 
 0.782
APX23928.1
Membrane protease subunit HflK; HflC and HflK could encode or regulate a protease.
  
 0.741
APX23925.1
HflK protein; HflC and HflK could encode or regulate a protease.
  
 0.736
APX21395.1
Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease.
  
 0.736
APX24313.1
PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.724
rplO
Large subunit ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.720
APX23927.1
Protease FtsH subunit HflC; HflC and HflK could regulate a protease.
  
 0.715
Your Current Organism:
Salipiger profundus
NCBI taxonomy Id: 1229727
Other names: CGMCC 1.12377, DSM 27508 [[Salipiger nanhaiensis]], Donghicola sp. ZH114, JCM 19383 [[Salipiger nanhaiensis]], KCTC 32468 [[Salipiger nanhaiensis]], LMG 27365, LMG:27365, S. profundus, Salipiger nanhaiensis, Salipiger nanhaiensis Dai et al. 2015, Salipiger sp. JLT2016, Thiobacimonas profunda, Thiobacimonas profunda Li et al. 2015 emend. Huang et al. 2017, strain JLT2016, strain ZH114 [[Salipiger nanhaiensis]]
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