STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucDSuccinyl-CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)    
Predicted Functional Partners:
CCM62086.1
Oxoglutarate decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.999
sucC
Succinyl-CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
CCM63223.1
Putative succinate dehydrogenase iron-sulfur protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.985
CCM62519.1
Putative succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.983
CCM63418.1
Putative Dihydrolipoyllysine-residue succinyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 0.978
sdhA
Succinate dehydrogenase/fumarate reductase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.977
CCM63224.1
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.977
CCM65841.1
Putative 2-oxoglutarate:ferredoxin oxidoreductase, alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.959
CCM65842.1
Putative 2-oxoglutarate:ferredoxin oxidoreductase, beta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 
 0.919
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.918
Your Current Organism:
Microthrix parvicella
NCBI taxonomy Id: 1229780
Other names: C. Microthrix parvicella RN1, Candidatus Microthrix parvicella RN1, Candidatus Microthrix parvicella str. RN1, Candidatus Microthrix parvicella strain RN1
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