STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCM63370.1Putative HhH-GPD family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (305 aa)    
Predicted Functional Partners:
CCM62087.1
Exodeoxyribonuclease III.
    
 0.933
CCM63369.1
Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.773
CCM63371.1
Putative AraC family transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.705
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 
0.684
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.603
CCM63372.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.549
CCM63303.1
HhH-GPD family protein.
  
 
 0.516
CCM63368.1
Putative Peptidase C11, clostripain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.491
recO
Putative DNA repair protein recO; Involved in DNA repair and RecF pathway recombination.
     
 0.491
polA
Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
  
 0.484
Your Current Organism:
Microthrix parvicella
NCBI taxonomy Id: 1229780
Other names: C. Microthrix parvicella RN1, Candidatus Microthrix parvicella RN1, Candidatus Microthrix parvicella str. RN1, Candidatus Microthrix parvicella strain RN1
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