STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metYHomocysteine synthase; Function of strongly homologous gene; enzyme. (441 aa)    
Predicted Functional Partners:
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 0.993
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.956
cbs
Putative Cystathionine beta-synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.890
cysG
Putative sulfite reductase (NADPH) hemoprotein beta-component; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.870
hom
Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.855
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
  
  
 0.851
sahH
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.819
pyrD
Fragment of dihydroorotate oxydase (part 2); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.817
dapC
Putative N-succinyldiaminopimelate aminotransferase DapC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
  0.802
ytkP
Putative cysteine synthase-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.799
Your Current Organism:
Microthrix parvicella
NCBI taxonomy Id: 1229780
Other names: C. Microthrix parvicella RN1, Candidatus Microthrix parvicella RN1, Candidatus Microthrix parvicella str. RN1, Candidatus Microthrix parvicella strain RN1
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