STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C273_02808Formate acetyltransferase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (250 aa)    
Predicted Functional Partners:
C273_02813
COG1882 Pyruvate-formate lyase.
 
 
 0.995
C273_00770
COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
    
 0.782
C273_01120
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.727
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
  0.561
C273_01115
COG0372 Citrate synthase; Belongs to the citrate synthase family.
     
 0.512
C273_03105
Putative phosphate butyryltransferase; COG0280 Phosphotransacetylase.
     
 0.483
eutD
COG0280 Phosphotransacetylase.
     
 0.483
C273_08826
Nitrite reductase [NAD(P)H] large subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
  
 0.403
Your Current Organism:
Staphylococcus massiliensis
NCBI taxonomy Id: 1229783
Other names: S. massiliensis S46, Staphylococcus massiliensis S46
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.