STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VPNG_07638ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (345 aa)    
Predicted Functional Partners:
VPNG_02748
NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
  
 
 0.932
VPNG_03362
Uncharacterized protein.
  
 
 0.879
VPNG_01694
Uncharacterized protein.
    
 0.630
VPNG_01809
Uncharacterized protein; Belongs to the phosphohexose mutase family.
 
 
    0.617
VPNG_01795
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
  
 0.530
VPNG_05477
SpoU_sub_bind domain-containing protein.
   
 
 0.502
VPNG_08773
Glutamate decarboxylase; Belongs to the group II decarboxylase family.
  
   0.481
VPNG_03351
ATP-grasp domain-containing protein.
  
 
 0.479
VPNG_07600
Uncharacterized protein.
    
  0.452
VPNG_05409
Glutamine amidotransferase type-1 domain-containing protein.
    
  0.452
Your Current Organism:
Cytospora leucostoma
NCBI taxonomy Id: 1230097
Other names: C. leucostoma, Leucostoma leucostoma, Leucostoma persoonii, Valsa leucostoma, Valsa persoonii
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