STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (381 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
C461_08299
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
 
 0.998
C461_13776
Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
  
 0.998
C461_02576
NADH-ubiquinone oxidoreductase chain 49kDa; COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit.
  
 
 0.997
C461_08314
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 
 0.996
C461_08304
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
 
 0.995
C461_08309
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
 
 0.995
C461_02661
2-methylcitrate synthase/citrate synthase II; COG0372 Citrate synthase.
  
 0.988
C461_03392
COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family.
   
  
 0.976
C461_10973
COG0538 Isocitrate dehydrogenases.
  
  
 0.973
Your Current Organism:
Halorubrum aidingense
NCBI taxonomy Id: 1230454
Other names: H. aidingense JCM 13560, Halorubrum aidingense JCM 13560, Halorubrum sp. 31-hong
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