STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (216 aa)    
Predicted Functional Partners:
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.999
dapH
Tetrahydrodipicolinate succinyltransferase domain-containing protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
 
 
 0.999
KHC91225.1
COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.981
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
 
 0.961
KHC91226.1
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
 
   
 0.947
KHC91230.1
COG0527 Aspartokinases; Belongs to the aspartokinase family.
 
 
 0.915
KHC90440.1
Aspartate kinase; COG0460 Homoserine dehydrogenase.
 
 
 0.881
KHC91232.1
Amidohydrolase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase.
 
   
 0.815
KHC90271.1
CBS domain-containing protein; COG0618 Exopolyphosphatase-related proteins; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
    0.800
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
  
    0.783
Your Current Organism:
Thermotoga sp. Mc24
NCBI taxonomy Id: 1231241
Other names: T. sp. Mc24
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