STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1-2Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (278 aa)    
Predicted Functional Partners:
L248_2369
Uncharacterized protein conserved in bacteria.
 
 
 0.999
L248_0007
Uncharacterized protein predicted to be involved in DNA repair.
  
 
 0.959
cas9
Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracr [...]
 
   
 0.925
L248_0252
Hup; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
    
   0.795
L248_1043
Hypothetical protein.
 
   
 0.713
L248_2817
Hypothetical protein.
    
 
 0.533
L248_2321
Hypothetical protein.
    
   0.418
L248_2909
Hypothetical protein; Predicted transcriptional regulator.
    
   0.418
L248_1477
Hypothetical protein; Predicted dehydrogenases and related proteins.
   
 
 0.404
L248_1494
Hypothetical protein.
   
 
 0.404
Your Current Organism:
Lactobacillus shenzhenensis
NCBI taxonomy Id: 1231336
Other names: L. shenzhenensis LY-73, Lactobacillus shenzhenensis KACC 16878, Lactobacillus shenzhenensis LY-73, Lactobacillus sp. KACC 16878
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.