STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OCGS_1668Low specificity L-threonine aldolase. (347 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.950
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.921
OCGS_1250
Threonine synthase.
   
 0.891
OCGS_0887
Sarcosine oxidase subunit alpha; Belongs to the GcvT family.
   
 0.884
OCGS_1666
Riboflavin biosynthesis protein RibF; Belongs to the ribF family.
     
 0.880
OCGS_0723
5-aminolevulinic acid synthase.
     
 0.876
OCGS_0886
Sarcosine oxidase subunit delta.
    
  0.858
OCGS_1667
Hypothetical protein; Belongs to the UPF0260 family.
       0.857
OCGS_1956
Aminomethyl transferase family protein; Belongs to the GcvT family.
   
 0.833
OCGS_2000
Serine--glyoxylate transaminase, putative.
    
 0.723
Your Current Organism:
Oceaniovalibus guishaninsula
NCBI taxonomy Id: 1231392
Other names: O. guishaninsula JLT2003, Oceaniovalibus guishaninsula JLT2003
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.