node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OCGS_0604 | leuA | OCGS_0604 | OCGS_1877 | acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.907 |
OCGS_0807 | OCGS_1837 | OCGS_0807 | OCGS_1837 | Acetolactate synthase, small subunit. | Branched-chain amino acid aminotransferase. | 0.604 |
OCGS_0807 | OCGS_2082 | OCGS_0807 | OCGS_2082 | Acetolactate synthase, small subunit. | Aminotransferase class IV, putative D-alanine aminotransferase. | 0.571 |
OCGS_0807 | ilvC | OCGS_0807 | OCGS_0390 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
OCGS_0807 | ilvD | OCGS_0807 | OCGS_1323 | Acetolactate synthase, small subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.815 |
OCGS_0807 | ilvE | OCGS_0807 | OCGS_1426 | Acetolactate synthase, small subunit. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.604 |
OCGS_0807 | leuA | OCGS_0807 | OCGS_1877 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.955 |
OCGS_0807 | leuB | OCGS_0807 | OCGS_1392 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.991 |
OCGS_0807 | leuC | OCGS_0807 | OCGS_1388 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.932 |
OCGS_0807 | leuD | OCGS_0807 | OCGS_1390 | Acetolactate synthase, small subunit. | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.938 |
OCGS_1837 | OCGS_0807 | OCGS_1837 | OCGS_0807 | Branched-chain amino acid aminotransferase. | Acetolactate synthase, small subunit. | 0.604 |
OCGS_1837 | OCGS_2082 | OCGS_1837 | OCGS_2082 | Branched-chain amino acid aminotransferase. | Aminotransferase class IV, putative D-alanine aminotransferase. | 0.753 |
OCGS_1837 | ilvC | OCGS_1837 | OCGS_0390 | Branched-chain amino acid aminotransferase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.411 |
OCGS_1837 | ilvD | OCGS_1837 | OCGS_1323 | Branched-chain amino acid aminotransferase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.887 |
OCGS_1837 | leuA | OCGS_1837 | OCGS_1877 | Branched-chain amino acid aminotransferase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.898 |
OCGS_1837 | leuB | OCGS_1837 | OCGS_1392 | Branched-chain amino acid aminotransferase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.451 |
OCGS_1837 | leuC | OCGS_1837 | OCGS_1388 | Branched-chain amino acid aminotransferase. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.424 |
OCGS_2082 | OCGS_0807 | OCGS_2082 | OCGS_0807 | Aminotransferase class IV, putative D-alanine aminotransferase. | Acetolactate synthase, small subunit. | 0.571 |
OCGS_2082 | OCGS_1837 | OCGS_2082 | OCGS_1837 | Aminotransferase class IV, putative D-alanine aminotransferase. | Branched-chain amino acid aminotransferase. | 0.753 |
OCGS_2082 | ilvD | OCGS_2082 | OCGS_1323 | Aminotransferase class IV, putative D-alanine aminotransferase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.892 |