STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpxDUDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (331 aa)    
Predicted Functional Partners:
lpxC/fabZ
Bifunctional enzyme lpxC/fabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
 0.999
lpxB
Lipid-A-disaccharide synthase; Homologs of previously reported genes of unknown function; Belongs to the LpxB family.
 
 
 0.995
lpxA
Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
0.991
lpxH
UDP-2,3-diacylglucosamine hydrolase.
  
  
 0.970
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.944
CAHE_0613
Putative uncharacterized protein; Homologs of previously reported genes of unknown function.
 
   
 0.812
rpsB
30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
  
 0.796
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.790
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
    0.786
CAHE_0182
Putative uncharacterized protein; Homologs of previously reported genes of unknown function.
  
    0.646
Your Current Organism:
Cardinium endosymbiont cEper1
NCBI taxonomy Id: 1231626
Other names: C. endosymbiont cEper1 of Encarsia pergandiella, Cardinium endosymbiont cEper1 of Encarsia pergandiella, Cardinium hertigii cEper1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.