STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y1Y0U1Uncharacterized protein. (86 aa)    
Predicted Functional Partners:
A0A1Y1Y9N0
Exonuclease-like protein.
  
 0.959
A0A1Y1ZQJ1
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.951
A0A1Y1ZNK1
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.945
A0A1Y1Z8Q4
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.926
A0A1Y1YL63
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.924
A0A1Y1ZP76
DUF1767 domain-containing protein.
    
 0.917
A0A1Y1Y0H9
AAA domain-domain-containing protein.
   
 0.915
A0A1Y1YTA5
P-loop containing nucleoside triphosphate hydrolase protein.
  
 0.910
A0A1Y1YUT8
Uncharacterized protein.
  
 0.907
A0A1Y1ZPZ3
ERCC4 domain-containing protein.
    
 0.905
Your Current Organism:
Clohesyomyces aquaticus
NCBI taxonomy Id: 1231657
Other names: C. aquaticus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.