STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GET3ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (333 aa)    
Predicted Functional Partners:
A0A1Y1ZI44
Uncharacterized protein.
    
 0.991
A0A1Y2A793
XPC-binding domain-domain-containing protein.
   
 0.973
A0A1Y1Y4T6
CHD5-like protein-domain-containing protein.
    
 0.962
GET1
Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
    
 0.962
A0A1Y1ZLP3
Uncharacterized protein.
    
 0.934
A0A1Y1ZBY0
F-box domain-containing protein.
   
 0.918
A0A1Y1YYE8
Phosphotyrosine protein phosphatase I superfamily.
    
 0.905
A0A1Y1ZY35
Uncharacterized protein.
    
 0.851
A0A1Y2ABI5
Putative ER-golgi SNARE complex subunit.
   
 0.840
A0A1Y1ZJY0
Transport protein-like protein sec22; Belongs to the synaptobrevin family.
   
 
 0.805
Your Current Organism:
Clohesyomyces aquaticus
NCBI taxonomy Id: 1231657
Other names: C. aquaticus
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