STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y1YPZ42-isopropylmalate synthase LeuA, allosteric domain-containing protein. (273 aa)    
Predicted Functional Partners:
A0A1Y1Y2Z7
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.956
A0A1Y1YKK9
ACT domain-containing protein.
  
 
 0.904
A0A1Y1Z8A9
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.899
A0A1Y1ZLV6
Aminotransferase.
  
 0.867
A0A1Y1ZMB3
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.867
A0A1Y1Y417
Acetolactate synthase.
  
 
 0.861
A0A1Y1ZKW6
Dihydroxy-acid/6-phosphogluconate dehydratase.
  
 
 0.843
A0A1Y1ZUT3
Dihydroxy-acid dehydratase-like protein.
  
 
 0.843
A0A1Y2A0S3
Aminotransferase.
  
 0.827
A0A1Y1YEE4
SCP2 sterol-binding domain-containing protein.
   
 
 0.804
Your Current Organism:
Clohesyomyces aquaticus
NCBI taxonomy Id: 1231657
Other names: C. aquaticus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.