STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y1ZY25DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (690 aa)    
Predicted Functional Partners:
A0A1Y1ZY67
DNA-dependent protein kinase.
    
 0.851
A0A1Y1YRT2
DNA ligase.
  
 0.847
A0A1Y2A9L0
DNA_LIGASE_A3 domain-containing protein.
  
 0.846
A0A1Y1Z747
DNA ligase.
  
 0.844
A0A1Y1ZZE4
DNA ligase.
  
 0.844
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.838
A0A1Y1Z4L1
Nickel/cobalt efflux system; Belongs to the NiCoT transporter (TC 2.A.52) family.
 
      0.833
A0A1Y1Y9N0
Exonuclease-like protein.
   
 0.821
A0A1Y1YAG0
Polynucleotide kinase 3 phosphatase-domain-containing protein.
    
 0.816
A0A1Y1ZPV2
Polynucleotide kinase 3 phosphatase-domain-containing protein.
    
 0.816
Your Current Organism:
Clohesyomyces aquaticus
NCBI taxonomy Id: 1231657
Other names: C. aquaticus
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