STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2A4Y6S-adenosyl-L-methionine-dependent methyltransferase. (433 aa)    
Predicted Functional Partners:
COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
   
 0.856
A0A1Y2A1L2
P-loop containing nucleoside triphosphate hydrolase protein.
     
 0.783
A0A1Y2A0Q7
Ubiquinone biosynthesis protein-like protein coq-8.
    
 
 0.746
A0A1Y1ZZC7
Uncharacterized protein.
     
 0.713
A0A1Y1ZEZ1
Quinone oxidoreductase.
     
 0.709
COQ4
Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.
    
 
 0.595
A0A1Y1YTH3
Decaprenyl-diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.
   
 
 0.593
A0A1Y1YIG4
BBE domain-containing protein.
    
 0.592
A0A1Y1YKM5
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
    
 0.592
A0A1Y1ZM80
FAD binding domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
    
 0.592
Your Current Organism:
Clohesyomyces aquaticus
NCBI taxonomy Id: 1231657
Other names: C. aquaticus
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