STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2A6B2Indoleamine 2,3-dioxygenase beta type. (418 aa)    
Predicted Functional Partners:
BNA5
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
   
 0.849
BNA5-2
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
   
 0.849
A0A1Y1ZD51
Pyridoxal phosphate-dependent transferase.
     
 0.777
A0A1Y1ZSH4
Indoleamine 2,3-dioxygenase family protein.
  
  
 
0.771
A0A1Y1YNK4
Dopa decarboxylase-like protein.
   
 
 0.765
A0A1Y2A207
Amine oxidase.
     
 0.765
A0A1Y1YWX4
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
     
 0.734
A0A1Y1YJE6
Acyl-CoA N-acyltransferase.
     
 0.729
A0A1Y1XYY5
Aminotran_1_2 domain-containing protein.
   
 
 0.690
A0A1Y1ZSR5
Aminotransferase.
   
 
 0.660
Your Current Organism:
Clohesyomyces aquaticus
NCBI taxonomy Id: 1231657
Other names: C. aquaticus
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