STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2AC32Bestrophin/UPF0187. (358 aa)    
Predicted Functional Partners:
A0A1Y1ZS26
2-oxoglutarate dehydrogenase E1 component mitochondrial.
    
 
 0.846
A0A1Y1YCF6
Ubiquitin-conjugating enzyme/RWD-like protein.
   
 0.799
A0A1Y2A9K3
BRCT domain-containing protein.
    
 0.775
A0A1Y2A664
Uncharacterized protein.
    
 0.703
A0A1Y1ZFC7
Ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.693
A0A1Y1ZRB3
Polyubiquitin.
    
 0.690
A0A1Y1ZYQ6
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 0.689
A0A1Y1ZHM7
Uncharacterized protein.
    
  0.673
A0A1Y1ZHV0
Uncharacterized protein.
    
  0.673
A0A1Y1ZIL9
Ubiquitin-like protein.
    
  0.673
Your Current Organism:
Clohesyomyces aquaticus
NCBI taxonomy Id: 1231657
Other names: C. aquaticus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.