STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACO03556.1Metallophosphoesterase; Identified by match to protein family HMM PF00149. (242 aa)    
Predicted Functional Partners:
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.817
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
       0.799
nusB
Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
       0.799
ACO04374.1
2-5A-dependent ribonuclease (2-5A-dependent RNase)(Ribonuclease L) (RNase L) (Ribonuclease 4); Identified by match to protein family HMM PF00023.
    
   0.660
ACO04496.1
Pfs, nacht and ankyrin domain protein; Identified by match to protein family HMM PF00023.
    
   0.660
ACO03140.1
Identified by match to protein family HMM PF00023.
    
   0.660
ACO04784.1
Ankyrin domain protein; Identified by match to protein family HMM PF00023.
    
   0.660
ACO03097.1
Transcriptional regulator; Identified by match to protein family HMM PF01041; Belongs to the DegT/DnrJ/EryC1 family.
  
    0.654
ACO03439.1
Oxidoreductase family, NAD-binding Rossmann fold protein; Identified by match to protein family HMM PF01408.
       0.646
ACO03902.1
Poly A polymerase; Identified by match to protein family HMM PF00571; match to protein family HMM PF01368; match to protein family HMM PF01743; match to protein family HMM PF02272; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
 
 0.508
Your Current Organism:
Persephonella marina
NCBI taxonomy Id: 123214
Other names: P. marina EX-H1, Persephonella marina EX-H1, Persephonella marina str. EX-H1, Persephonella marina strain EX-H1, bacterium EX-H1
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