STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfoProbable endonuclease 4 (Endonuclease IV)(Endodeoxyribonuclease IV); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. (285 aa)    
Predicted Functional Partners:
ACO03858.1
Beta-lactamase domain protein; Identified by match to protein family HMM PF00753.
  
    0.776
accC_1
acetyl-CoA carboxylase, biotin carboxylase subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02222; match to protein family HMM PF02785; match to protein family HMM PF02786; match to protein family HMM PF08443; match to protein family HMM TIGR00514.
       0.773
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.587
nth-2
Probable endonuclease III (DNA-(apurinic orapyrimidinic site) lyase); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.587
ACO04507.1
Glycoside hydrolase family 23; Identified by match to protein family HMM PF01464; match to protein family HMM PF01476.
       0.587
ACO04297.1
Type IV pilus assembly protein TapB; Identified by match to protein family HMM PF00437; match to protein family HMM PF05157.
       0.557
ACO03029.1
Twitching mobility protein; Identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420.
       0.550
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
  
    0.537
pilC
Type IV pilus biogenesis protein PilC; Identified by match to protein family HMM PF00482.
       0.527
ACO03687.1
Octaprenyl-diphosphate synthase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
       0.524
Your Current Organism:
Persephonella marina
NCBI taxonomy Id: 123214
Other names: P. marina EX-H1, Persephonella marina EX-H1, Persephonella marina str. EX-H1, Persephonella marina strain EX-H1, bacterium EX-H1
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