STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepACytosol aminopeptidase (Leucine aminopeptidase) (LAP)(Leucyl aminopeptidase); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (497 aa)    
Predicted Functional Partners:
ACO04046.1
Gamma-glutamyltransferase; Identified by match to protein family HMM PF01019.
  
  
 0.922
ggt
Gamma-glutamyltransferase; Identified by match to protein family HMM PF01019; match to protein family HMM TIGR00066.
     
 0.912
ACO04439.1
Carboxylate-amine ligase Francci3_0693; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.830
ACO02975.1
Aspartate aminotransferase; Identified by match to protein family HMM PF00155.
   
  0.814
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
  0.720
ACO03460.1
Putative peptidase M1, membrane alanine aminopeptidase; Identified by match to protein family HMM PF00595; match to protein family HMM PF01433; match to protein family HMM PF04187.
  
 
 0.563
ACO03011.1
3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III C; Identified by match to protein family HMM PF02797; match to protein family HMM PF08541.
       0.552
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.505
ACO04633.1
Xaa-Pro dipeptidase (X-Pro dipeptidase) (Prolinedipeptidase) (Prolidase) (Imidodipeptidase); Identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Belongs to the peptidase M24B family.
  
 
 0.456
Your Current Organism:
Persephonella marina
NCBI taxonomy Id: 123214
Other names: P. marina EX-H1, Persephonella marina EX-H1, Persephonella marina str. EX-H1, Persephonella marina strain EX-H1, bacterium EX-H1
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