node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADIMK_0167 | ADIMK_3218 | ADIMK_0167 | ADIMK_3218 | Lipoate-protein ligase A. | Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. | 0.691 |
ADIMK_0167 | gcvH | ADIMK_0167 | ADIMK_2232 | Lipoate-protein ligase A. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.947 |
ADIMK_1414 | ADIMK_1426 | ADIMK_1414 | ADIMK_1426 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Aminomethyltransferase; Belongs to the GcvT family. | 0.676 |
ADIMK_1414 | ADIMK_2034 | ADIMK_1414 | ADIMK_2034 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | 0.835 |
ADIMK_1414 | ADIMK_3218 | ADIMK_1414 | ADIMK_3218 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. | 0.771 |
ADIMK_1414 | gcvH | ADIMK_1414 | ADIMK_2232 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.924 |
ADIMK_1414 | gcvP | ADIMK_1414 | ADIMK_4158 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.995 |
ADIMK_1414 | glyA | ADIMK_1414 | ADIMK_0750 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.898 |
ADIMK_1414 | glyA-2 | ADIMK_1414 | ADIMK_2031 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.898 |
ADIMK_1418 | ADIMK_1426 | ADIMK_1418 | ADIMK_1426 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Aminomethyltransferase; Belongs to the GcvT family. | 0.682 |
ADIMK_1418 | ADIMK_3218 | ADIMK_1418 | ADIMK_3218 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. | 0.621 |
ADIMK_1418 | ADIMK_4161 | ADIMK_1418 | ADIMK_4161 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Aminomethyltransferase (glycine cleavage system T protein). | 0.703 |
ADIMK_1418 | gcvH | ADIMK_1418 | ADIMK_2232 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.981 |
ADIMK_1418 | gcvP | ADIMK_1418 | ADIMK_4158 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.993 |
ADIMK_1418 | glyA | ADIMK_1418 | ADIMK_0750 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.730 |
ADIMK_1418 | glyA-2 | ADIMK_1418 | ADIMK_2031 | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.728 |
ADIMK_1426 | ADIMK_1414 | ADIMK_1426 | ADIMK_1414 | Aminomethyltransferase; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | 0.676 |
ADIMK_1426 | ADIMK_1418 | ADIMK_1426 | ADIMK_1418 | Aminomethyltransferase; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | 0.682 |
ADIMK_1426 | ADIMK_2034 | ADIMK_1426 | ADIMK_2034 | Aminomethyltransferase; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit; Belongs to the GcvT family. | 0.613 |
ADIMK_1426 | ADIMK_3218 | ADIMK_1426 | ADIMK_3218 | Aminomethyltransferase; Belongs to the GcvT family. | Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. | 0.760 |