SEK80330.1 protein (Nitrosovibrio tenuis) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

SEK80330.1

Wzt C-terminal domain-containing protein. (89 aa)

Predicted Functional Partners:

SEK36195.1

0.996

SEK80251.1

0.817

SEK80174.1

0.784

SEK26024.1

0.782

SEK29882.1

0.782

SEK80212.1

0.780

SEK80292.1

0.779

SEL48101.1

0.752

SEK36162.1

0.677

SEK26833.1

0.564

Your Current Organism:

Nitrosovibrio tenuis

NCBI taxonomy Id: 1233
Other names: N. tenuis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SEK26024.1	SEK26833.1	SAMN05216387_1014	SAMN05216387_10124	Polysaccharide export outer membrane protein.	Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.	0.674
SEK26024.1	SEK29882.1	SAMN05216387_1014	SAMN05216387_10195	Polysaccharide export outer membrane protein.	Polysaccharide export outer membrane protein.	0.754
SEK26024.1	SEK36162.1	SAMN05216387_1014	SAMN05216387_101246	Polysaccharide export outer membrane protein.	ABC-2 type transport system ATP-binding protein/lipopolysaccharide transport system ATP-binding protein.	0.782
SEK26024.1	SEK36195.1	SAMN05216387_1014	SAMN05216387_101247	Polysaccharide export outer membrane protein.	Lipopolysaccharide transport system permease protein.	0.866
SEK26024.1	SEK80330.1	SAMN05216387_1014	SAMN05216387_10366	Polysaccharide export outer membrane protein.	Wzt C-terminal domain-containing protein.	0.782
SEK26833.1	SEK26024.1	SAMN05216387_10124	SAMN05216387_1014	Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.	Polysaccharide export outer membrane protein.	0.674
SEK26833.1	SEK29882.1	SAMN05216387_10124	SAMN05216387_10195	Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.	Polysaccharide export outer membrane protein.	0.674
SEK26833.1	SEK36162.1	SAMN05216387_10124	SAMN05216387_101246	Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.	ABC-2 type transport system ATP-binding protein/lipopolysaccharide transport system ATP-binding protein.	0.564
SEK26833.1	SEK36195.1	SAMN05216387_10124	SAMN05216387_101247	Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.	Lipopolysaccharide transport system permease protein.	0.618
SEK26833.1	SEK80174.1	SAMN05216387_10124	SAMN05216387_10362	Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.	dTDP-4-amino-4,6-dideoxygalactose transaminase; Belongs to the DegT/DnrJ/EryC1 family.	0.520
SEK26833.1	SEK80251.1	SAMN05216387_10124	SAMN05216387_10364	Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.	Methyltransferase domain-containing protein.	0.634
SEK26833.1	SEK80330.1	SAMN05216387_10124	SAMN05216387_10366	Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.	Wzt C-terminal domain-containing protein.	0.564
SEK29882.1	SEK26024.1	SAMN05216387_10195	SAMN05216387_1014	Polysaccharide export outer membrane protein.	Polysaccharide export outer membrane protein.	0.754
SEK29882.1	SEK26833.1	SAMN05216387_10195	SAMN05216387_10124	Polysaccharide export outer membrane protein.	Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.	0.674
SEK29882.1	SEK36162.1	SAMN05216387_10195	SAMN05216387_101246	Polysaccharide export outer membrane protein.	ABC-2 type transport system ATP-binding protein/lipopolysaccharide transport system ATP-binding protein.	0.782
SEK29882.1	SEK36195.1	SAMN05216387_10195	SAMN05216387_101247	Polysaccharide export outer membrane protein.	Lipopolysaccharide transport system permease protein.	0.866
SEK29882.1	SEK80330.1	SAMN05216387_10195	SAMN05216387_10366	Polysaccharide export outer membrane protein.	Wzt C-terminal domain-containing protein.	0.782
SEK36162.1	SEK26024.1	SAMN05216387_101246	SAMN05216387_1014	ABC-2 type transport system ATP-binding protein/lipopolysaccharide transport system ATP-binding protein.	Polysaccharide export outer membrane protein.	0.782
SEK36162.1	SEK26833.1	SAMN05216387_101246	SAMN05216387_10124	ABC-2 type transport system ATP-binding protein/lipopolysaccharide transport system ATP-binding protein.	Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.	0.564
SEK36162.1	SEK29882.1	SAMN05216387_101246	SAMN05216387_10195	ABC-2 type transport system ATP-binding protein/lipopolysaccharide transport system ATP-binding protein.	Polysaccharide export outer membrane protein.	0.782

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Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0060480

Lung goblet cell differentiation

2 of 3

3.09

0.85

0.0293

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:37298509

(2023) The Regulated Secretion and Models of Intracellular Transport: The Goblet Cell as an Example.

3 of 21

2.42

1.01

0.0139

PMID:31871532

(2019) Calcium-activated chloride channel regulator 1 (CLCA1): More than a regulator of chloride transport and mucus production.

3 of 30

2.26

0.94

0.0187

PMID:19468668

(2009) Differential gene expression in normal esophagus and Barretts esophagus.

3 of 35

2.2

0.92

0.0193

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:33710

Calcium-activated chloride channel N terminal, and P-type trefoil domain

3 of 6

2.96

2.39

4.54e-05

CL:31027

O-linked glycosylation of mucins

3 of 27

2.31

1.73

0.00054

CL:33682

Mostly uncharacterized, incl. Post-translational modification: synthesis of GPI-anchored proteins, and Cobalamin (Cbl, vitamin B12) transport and metabolism

4 of 142

1.71

1.49

0.00062

CL:31030

Termination of O-glycan biosynthesis

2 of 11

2.52

1.15

0.0080

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

CFA-913709

O-linked glycosylation of mucins

4 of 53

2.14

2.28

2.96e-05

Tissue Expression (TISSUES)

tissue

description

count in network

strength

signal

false discovery rate

BTO:0000765

Exocrine gland

3 of 81

1.83

0.99

0.0114

BTO:0000648

Intestine

5 of 524

1.24

0.81

0.0100

BTO:0001158

Rectum

2 of 29

2.1

0.81

0.0317

BTO:0000269

Colon

3 of 147

1.57

0.78

0.0258

BTO:0001388

Trachea

2 of 37

2.0

0.72

0.0448

(more ...)

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