STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (296 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
SKC63309.1
2-oxoglutarate dehydrogenase E1 component.
 0.988
SKC62332.1
Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 0.986
SKC62343.1
Succinate dehydrogenase subunit A.
 0.972
SKC51165.1
Glutamate synthase (NADH) large subunit.
   
 
 0.967
SKC49844.1
2-oxoglutarate dehydrogenase E2 component.
 
 0.966
SKC62361.1
Succinate dehydrogenase subunit C.
  
 
 0.965
SKC35055.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.949
SKC42009.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.916
SKC62350.1
Succinate dehydrogenase subunit D.
  
 
 0.913
Your Current Organism:
Okibacterium fritillariae
NCBI taxonomy Id: 123320
Other names: Curtibacterium sp. VKM Ac-2059, Curtibacterium sp. VKM Ac-2062, Curtobacterium sp. VKM Ac-2059, Curtobacterium sp. VKM Ac-2062, IFO 16404, JCM 12284, NBRC 16404, O. fritillariae, Okibacterium fritillariae Evtushenko et al. 2002, VKM Ac-2059
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.