STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKC66996.12-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. (181 aa)    
Predicted Functional Partners:
SKC67002.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.999
SKC67010.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
folE
GTP cyclohydrolase I.
 
  
 0.995
ribA
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
    
 0.893
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.832
SKC66954.1
Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains.
       0.826
SKC66961.1
Putative membrane protein.
       0.826
SKC66968.1
Hypothetical protein.
       0.826
SKC66975.1
Protein of unknown function.
       0.826
SKC66945.1
Hypothetical protein.
     
 0.799
Your Current Organism:
Okibacterium fritillariae
NCBI taxonomy Id: 123320
Other names: Curtibacterium sp. VKM Ac-2059, Curtibacterium sp. VKM Ac-2062, Curtobacterium sp. VKM Ac-2059, Curtobacterium sp. VKM Ac-2062, IFO 16404, JCM 12284, NBRC 16404, O. fritillariae, Okibacterium fritillariae Evtushenko et al. 2002, VKM Ac-2059
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