STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C683_0249Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (423 aa)    
Predicted Functional Partners:
C683_0247
Hydroxymethylglutaryl-CoA synthase.
 
 0.991
C683_0248
3-ketoacyl-CoA thiolase / Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.983
C683_0405
Mevalonate kinase.
 0.979
C683_0930
Putative prenyltransferase; Contains 1,4-dihydroxy-2-naphthoate octaprenyltransferase domain.
   
 
 0.770
C683_0404
Diphosphomevalonate decarboxylase.
 
 
 0.766
fni
Isopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
    
 0.675
C683_0704
Octaprenyl-diphosphate synthase; Dimethylallyltransferase / Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.561
C683_0403
Phosphomevalonate kinase.
  
 0.525
Your Current Organism:
Catellicoccus marimammalium
NCBI taxonomy Id: 1234409
Other names: C. marimammalium M35/04/3, Catellicoccus marimammalium M35/04/3
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.