STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (360 aa)    
Predicted Functional Partners:
C683_0815
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.999
C683_0816
Pyruvate dehydrogenase E1 component beta subunit.
 0.999
C683_0814
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex.
 
 0.994
C683_0235
Pyruvate-flavodoxin oxidoreductase.
  
 0.975
C683_0475
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.917
C683_0457
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.879
C683_0674
Pyruvate formate-lyase.
   
 
 0.870
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.868
C683_1069
Fructose-bisphosphate aldolase class II.
    
 0.867
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.854
Your Current Organism:
Catellicoccus marimammalium
NCBI taxonomy Id: 1234409
Other names: C. marimammalium M35/04/3, Catellicoccus marimammalium M35/04/3
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