STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C809_02121RpiB/LacA/LacB family sugar-phosphate isomerase. (143 aa)    
Predicted Functional Partners:
C809_01751
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
 
 0.982
C809_00768
Hypothetical protein; Belongs to the UPF0340 family.
 
  
 0.977
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
  0.963
C809_02108
Transketolase.
 
 
 0.959
C809_02107
Transketolase.
 
  
 0.954
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
     
 0.947
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
   
 
  0.947
C809_03481
Phosphoglucomutase.
     
 0.944
C809_01207
Altronate hydrolase.
     
 0.942
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
  
 0.933
Your Current Organism:
Lachnospiraceae bacterium MD335
NCBI taxonomy Id: 1235793
Other names: L. bacterium MD335, Lachnospiraceae bacterium COE1
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