STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDC27614.1Pyruvate dehydrogenase E1 component beta subunit. (325 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
SDC43702.1
Branched-chain alpha-keto acid dehydrogenase E1 component.
 0.999
pdhA-2
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
SDC27639.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.998
SDC84544.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.991
SDC84565.1
Dihydrolipoamide dehydrogenase.
 
 0.987
SDC43685.1
Dihydrolipoamide dehydrogenase.
 
 0.985
SDC43752.1
2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase).
 0.967
SDC59579.1
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.956
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.956
Your Current Organism:
Melghirimyces thermohalophilus
NCBI taxonomy Id: 1236220
Other names: CCUG 60050, DSM 45514, M. thermohalophilus, Melghirimyces sp. Nari11A, Melghirimyces thermohalophilus Addou et al. 2013, strain Nari11A
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