STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tgtAArchaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (652 aa)    
Predicted Functional Partners:
cmk
tRNA pseudouridine 55 synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
  
 0.862
AGI85932.1
Archaeosine tRNA-ribosyltransferase type 2.
 
 
0.825
AGI85118.1
Queuosine biosynthesis QueD, PTPS-I.
 
   
 0.802
queC
Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
   
 0.802
AGI84900.1
tRNA (1-methyladenosine) methyltransferase.
  
  
 0.764
AGI85335.1
Hypothetical protein.
       0.654
queE
Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
     
 0.648
AGI85405.1
Hypothetical protein.
     
 0.648
AGI85010.1
tRNA-(G10-N2) methyltransferase; tRNA-(G10-N2) dimethyltransferase.
  
  
 0.637
AGI86370.1
tRNA cytosine methylase Pos56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
 
     0.633
Your Current Organism:
Methanomethylophilus alvus
NCBI taxonomy Id: 1236689
Other names: C. Methanomethylophilus alvus Mx1201, Candidatus Methanomethylophilus alvus Mx1201, archaeon Mx1201
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.