STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (309 aa)    
Predicted Functional Partners:
AGI85686.2
Methionine gamma-lyase.
   
 
 0.910
AGI86059.1
Homoserine dehydrogenase.
   
 
 0.902
AGI85351.1
O-acetylhomoserine sulfhydrylase / O-succinylhomoserine sulfhydrylase.
    
  0.900
AGI86226.1
Aspartokinase; Belongs to the aspartokinase family.
 
 
  
 0.882
glyA
Serine hydroxymethyltransferase / H4MPt-dependent SHMT; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.848
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
 0.831
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 
 0.821
AGI84784.2
Tryptophan synthase beta chain like protein.
     
  0.800
AGI86342.1
Phosphoserine phosphatase.
    
  0.800
AGI85387.1
Endoribonuclease L-PSP.
  
  
 0.779
Your Current Organism:
Methanomethylophilus alvus
NCBI taxonomy Id: 1236689
Other names: C. Methanomethylophilus alvus Mx1201, Candidatus Methanomethylophilus alvus Mx1201, archaeon Mx1201
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.