STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGI86278.1Hypothetical protein. (123 aa)    
Predicted Functional Partners:
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
      0.945
hisI
Phosphoribosyl-AMP cyclohydrolase / Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
     
 0.870
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.700
AGI85410.1
Hypothetical protein.
  
  
 0.681
AGI86280.1
Putative single-stranded-DNA-specific exonuclease.
  
  
 0.655
rps15
SSU ribosomal protein S13e (S15p).
  
    0.554
AGI86275.1
Hypothetical protein.
       0.553
msrA
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.471
AGI84855.1
Hypothetical protein; FIG00516948.
  
  
 0.432
pyrD
Dihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
  
 0.426
Your Current Organism:
Methanomethylophilus alvus
NCBI taxonomy Id: 1236689
Other names: C. Methanomethylophilus alvus Mx1201, Candidatus Methanomethylophilus alvus Mx1201, archaeon Mx1201
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.