node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C900_00131 | C900_05077 | C900_00131 | C900_05077 | Hypothetical protein. | Tryptophan 2,3-dioxygenase. | 0.647 |
C900_00131 | kmo | C900_00131 | C900_03222 | Hypothetical protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.445 |
C900_00131 | kynU | C900_00131 | C900_03221 | Hypothetical protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.670 |
C900_00859 | C900_05077 | C900_00859 | C900_05077 | Kynurenine formamidase, bacterial. | Tryptophan 2,3-dioxygenase. | 0.797 |
C900_00859 | kmo | C900_00859 | C900_03222 | Kynurenine formamidase, bacterial. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.434 |
C900_00859 | kynU | C900_00859 | C900_03221 | Kynurenine formamidase, bacterial. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.865 |
C900_01368 | C900_05077 | C900_01368 | C900_05077 | Putative cyclase. | Tryptophan 2,3-dioxygenase. | 0.797 |
C900_01368 | kmo | C900_01368 | C900_03222 | Putative cyclase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.434 |
C900_01368 | kynU | C900_01368 | C900_03221 | Putative cyclase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.840 |
C900_03218 | C900_03220 | C900_03218 | C900_03220 | 3-oxoacyl-[acyl-carrier protein] reductase. | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.513 |
C900_03218 | C900_03332 | C900_03218 | C900_03332 | 3-oxoacyl-[acyl-carrier protein] reductase. | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase. | 0.528 |
C900_03218 | kmo | C900_03218 | C900_03222 | 3-oxoacyl-[acyl-carrier protein] reductase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.594 |
C900_03218 | kynU | C900_03218 | C900_03221 | 3-oxoacyl-[acyl-carrier protein] reductase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.624 |
C900_03218 | nbaC | C900_03218 | C900_03219 | 3-oxoacyl-[acyl-carrier protein] reductase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.635 |
C900_03220 | C900_03218 | C900_03220 | C900_03218 | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 3-oxoacyl-[acyl-carrier protein] reductase. | 0.513 |
C900_03220 | kmo | C900_03220 | C900_03222 | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.774 |
C900_03220 | kynU | C900_03220 | C900_03221 | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.777 |
C900_03220 | nbaC | C900_03220 | C900_03219 | Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.773 |
C900_03332 | C900_03218 | C900_03332 | C900_03218 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase. | 3-oxoacyl-[acyl-carrier protein] reductase. | 0.528 |
C900_03332 | kmo | C900_03332 | C900_03222 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.813 |