STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (611 aa)    
Predicted Functional Partners:
C882_4213
2-oxoglutarate oxidoreductase, alpha subunit.
   
 
 0.982
C882_1234
2-oxoglutarate oxidoreductase, alpha subunit.
   
 
 0.971
C882_1839
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.902
C882_0949
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 
 0.896
C882_4147
Citrate synthase (si); Belongs to the citrate synthase family.
   
 
 0.896
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.895
C882_0143
Pyruvate carboxyl transferase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.893
C882_0009
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.892
C882_4214
2-oxoglutarate oxidoreductase, beta subunit.
   
 
 0.880
C882_2798
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.873
Your Current Organism:
Caenispirillum salinarum
NCBI taxonomy Id: 1238182
Other names: C. salinarum AK4, Caenispirillum salinarum AK4, Caenispirillum salinarum JCM 17360, Caenispirillum salinarum MTCC 10963, Caenispirillum sp. AK4
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