STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C882_3287ABC transporter involved in cytochrome c biogenesis, CcmB subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (221 aa)    
Predicted Functional Partners:
ccmC
Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.999
ccmA
ABC transporter involved in cytochrome c biogenesis, ATPase component CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 0.999
C882_3285
Hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
  
 
 0.986
ccmE
Cytochrome c-type biogenesis protein CcmE, heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.973
C882_3282
Thiol disulfide oxidoreductase.
 
  
 0.902
C882_3283
Cytochrome c heme lyase subunit CcmF.
 
  
 0.885
C882_3281
Cytochrome c heme lyase subunit CcmL; Possible subunit of a heme lyase.
 
   
 0.874
C882_3280
Cytochrome c heme lyase subunit CcmH.
 
   
 0.848
C882_0635
Cytochrome c heme lyase subunit CcmF.
 
  
 0.845
C882_0636
Cytochrome c heme lyase subunit CcmL; Possible subunit of a heme lyase.
 
   
 0.834
Your Current Organism:
Caenispirillum salinarum
NCBI taxonomy Id: 1238182
Other names: C. salinarum AK4, Caenispirillum salinarum AK4, Caenispirillum salinarum JCM 17360, Caenispirillum salinarum MTCC 10963, Caenispirillum sp. AK4
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