C882_4432 protein (Caenispirillum salinarum)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

C882_4432

Acyl-CoA dehydrogenase. (594 aa)

Predicted Functional Partners:

C882_2413

0.987

C882_4103

0.971

C882_1542

0.955

C882_0269

0.952

C882_0270

0.943

C882_0273

0.933

C882_3458

0.901

C882_1824

0.860

C882_2085

0.860

C882_0917

0.857

Your Current Organism:

Caenispirillum salinarum

NCBI taxonomy Id: 1238182
Other names: C. salinarum AK4, Caenispirillum salinarum AK4, Caenispirillum salinarum JCM 17360, Caenispirillum salinarum MTCC 10963, Caenispirillum sp. AK4

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
C882_0269	C882_0270	Malonyl CoA-acyl carrier protein transacylase.	Malonyl CoA-acyl carrier protein transacylase.	0.999
C882_0269	C882_0273	Malonyl CoA-acyl carrier protein transacylase.	Long-chain-fatty-acid--CoA ligase.	0.999
C882_0269	C882_0917	Malonyl CoA-acyl carrier protein transacylase.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.950
C882_0269	C882_1542	Malonyl CoA-acyl carrier protein transacylase.	Hypothetical protein.	0.992
C882_0269	C882_1824	Malonyl CoA-acyl carrier protein transacylase.	Enoyl-CoA hydratase.	0.977
C882_0269	C882_2085	Malonyl CoA-acyl carrier protein transacylase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.977
C882_0269	C882_2413	Malonyl CoA-acyl carrier protein transacylase.	Electron transfer flavoprotein.	0.947
C882_0269	C882_3458	Malonyl CoA-acyl carrier protein transacylase.	Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.950
C882_0269	C882_4103	Malonyl CoA-acyl carrier protein transacylase.	Enoyl-CoA hydratase.	0.992
C882_0269	C882_4432	Malonyl CoA-acyl carrier protein transacylase.	Acyl-CoA dehydrogenase.	0.952
C882_0270	C882_0269	Malonyl CoA-acyl carrier protein transacylase.	Malonyl CoA-acyl carrier protein transacylase.	0.999
C882_0270	C882_0273	Malonyl CoA-acyl carrier protein transacylase.	Long-chain-fatty-acid--CoA ligase.	0.999
C882_0270	C882_0917	Malonyl CoA-acyl carrier protein transacylase.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.906
C882_0270	C882_1542	Malonyl CoA-acyl carrier protein transacylase.	Hypothetical protein.	0.983
C882_0270	C882_1824	Malonyl CoA-acyl carrier protein transacylase.	Enoyl-CoA hydratase.	0.937
C882_0270	C882_2085	Malonyl CoA-acyl carrier protein transacylase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.937
C882_0270	C882_2413	Malonyl CoA-acyl carrier protein transacylase.	Electron transfer flavoprotein.	0.955
C882_0270	C882_3458	Malonyl CoA-acyl carrier protein transacylase.	Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.906
C882_0270	C882_4103	Malonyl CoA-acyl carrier protein transacylase.	Enoyl-CoA hydratase.	0.983
C882_0270	C882_4432	Malonyl CoA-acyl carrier protein transacylase.	Acyl-CoA dehydrogenase.	0.943

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Network Stats

number of nodes:

9

number of edges:

25

average node degree:

5.56

avg. local clustering coefficient:

0.702

expected number of edges:

8

PPI enrichment p-value:

1.2e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031952

Regulation of protein autophosphorylation

3 of 10

3.16

3.01

7.58e-06

GO:0050730

Regulation of peptidyl-tyrosine phosphorylation

3 of 37

2.59

2.23

0.00013

GO:0006469

Negative regulation of protein kinase activity

3 of 41

2.55

2.23

0.00013

GO:0051338

Regulation of transferase activity

4 of 452

1.63

1.5

0.00063

GO:0007167

Enzyme-linked receptor protein signaling pathway

3 of 308

1.67

1.1

0.0071

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019903

Protein phosphatase binding

6 of 59

2.69

6.49

1.37e-12

GO:0019901

Protein kinase binding

6 of 217

2.13

4.32

8.73e-10

GO:0019899

Enzyme binding

7 of 932

1.56

2.56

2.76e-08

GO:0042802

Identical protein binding

6 of 647

1.65

2.54

2.81e-07

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005634

Nucleus

7 of 5174

0.81

0.57

0.0087

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:29607

Major vault protein

9 of 24

3.26

14.16

1.08e-25

CL:29643

Regulation of protein autophosphorylation, and Actin

4 of 6

3.51

5.66

2.52e-10

CL:29610

Major vault protein

4 of 14

3.14

4.99

2.75e-09

CL:29612

Major vault protein

2 of 6

3.21

1.8

0.00090

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6798695

Neutrophil degranulation

6 of 514

1.75

2.76

2.30e-07

MAP-168249

Innate Immune System

6 of 1254

1.36

1.59

2.26e-05

MAP-168256

Immune System

6 of 2765

1.02

0.84

0.0016

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF11978

Shoulder domain

2 of 13

2.87

1.28

0.0068

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039059

Major vault protein

8 of 27

3.16

11.61

3.09e-21

IPR021870

Major vault protein, shoulder domain

2 of 13

2.87

1.2

0.0092

IPR036013

Band 7/SPFH domain superfamily

2 of 19

2.71

1.12

0.0122

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