node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OOS03529.1 | dcd | B0188_06705 | B0188_03800 | Nucleoside triphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.630 |
OOS03529.1 | dut | B0188_06705 | B0188_04045 | Nucleoside triphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.521 |
OOS03529.1 | pyrG | B0188_06705 | B0188_10200 | Nucleoside triphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.666 |
OOS03529.1 | udk | B0188_06705 | B0188_03805 | Nucleoside triphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.587 |
OOS05542.1 | OOS05543.1 | B0188_03790 | B0188_03795 | Sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.791 |
OOS05542.1 | dcd | B0188_03790 | B0188_03800 | Sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.791 |
OOS05542.1 | udk | B0188_03790 | B0188_03805 | Sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.768 |
OOS05543.1 | OOS05542.1 | B0188_03795 | B0188_03790 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.791 |
OOS05543.1 | dcd | B0188_03795 | B0188_03800 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.795 |
OOS05543.1 | udk | B0188_03795 | B0188_03805 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.790 |
OOS05785.1 | dcd | B0188_03120 | B0188_03800 | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.822 |
OOS05785.1 | dut | B0188_03120 | B0188_04045 | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.875 |
OOS05785.1 | ndk | B0188_03120 | B0188_00850 | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.819 |
OOS05785.1 | pyrG | B0188_03120 | B0188_10200 | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.648 |
OOS05785.1 | thyA | B0188_03120 | B0188_07415 | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.766 |
OOS05785.1 | tmk | B0188_03120 | B0188_08020 | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.716 |
dcd | OOS03529.1 | B0188_03800 | B0188_06705 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside triphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.630 |
dcd | OOS05542.1 | B0188_03800 | B0188_03790 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.791 |
dcd | OOS05543.1 | B0188_03800 | B0188_03795 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.795 |
dcd | OOS05785.1 | B0188_03800 | B0188_03120 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.822 |