node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OOS02968.1 | OOS03419.1 | B0188_07045 | B0188_06120 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.835 |
OOS02968.1 | OOS06389.1 | B0188_07045 | B0188_02325 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.859 |
OOS02968.1 | OOS07636.1 | B0188_07045 | B0188_00765 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.836 |
OOS02968.1 | cysS | B0188_07045 | B0188_00700 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.651 |
OOS02968.1 | glyA | B0188_07045 | B0188_09020 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Peroxidase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.867 |
OOS02968.1 | ilvA | B0188_07045 | B0188_06140 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.942 |
OOS02968.1 | metXA | B0188_07045 | B0188_03275 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.987 |
OOS02968.1 | trpF | B0188_07045 | B0188_01210 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.873 |
OOS03419.1 | OOS02968.1 | B0188_06120 | B0188_07045 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.835 |
OOS03419.1 | OOS06389.1 | B0188_06120 | B0188_02325 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.686 |
OOS03419.1 | OOS07636.1 | B0188_06120 | B0188_00765 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.989 |
OOS03419.1 | cysS | B0188_06120 | B0188_00700 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.971 |
OOS03419.1 | glyA | B0188_06120 | B0188_09020 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peroxidase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.671 |
OOS03419.1 | gpsA | B0188_06120 | B0188_06115 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.809 |
OOS03419.1 | ilvA | B0188_06120 | B0188_06140 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.739 |
OOS03419.1 | lpxD | B0188_06120 | B0188_04365 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.660 |
OOS03419.1 | metXA | B0188_06120 | B0188_03275 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.663 |
OOS03419.1 | trpF | B0188_06120 | B0188_01210 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.825 |
OOS06389.1 | OOS02968.1 | B0188_02325 | B0188_07045 | Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.859 |
OOS06389.1 | OOS03419.1 | B0188_02325 | B0188_06120 | Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.686 |