STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spt4DNA-directed RNA polymerase subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (65 aa)    
Predicted Functional Partners:
ERG99531.1
Early transcription elongation factor of RNA pol II, NGN section.
   
 
 0.999
ERG99730.1
DNA-directed RNA polymerase, rpoE.
 
 
 0.986
ERG99728.1
Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
    0.909
ERG99731.1
PilTVapc superfamily protein.
 
     0.868
rps24e
Ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family.
 
    0.798
eif2g
Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
    0.770
ERG99726.1
Metallohydrolase, glycoprotease/Kae1 family.
       0.699
ERG99725.1
Hypothetical protein.
       0.679
priS
DNA primase, eukaryotic-type, small subunit, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extens [...]
  
   
 0.645
ERG98639.1
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.633
Your Current Organism:
Haloquadratum sp. J07HQX50
NCBI taxonomy Id: 1238426
Other names: H. sp. J07HQX50
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