STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (284 aa)    
Predicted Functional Partners:
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 0.999
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.965
ERH00034.1
Ornithine/acetylornithine aminotransferase.
   
 0.868
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
   
 0.788
ERG99167.1
Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.766
guaAB
GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; Catalyzes the synthesis of GMP from XMP.
   
 
 0.766
ERG99298.1
Asparagine synthase (glutamine-hydrolyzing).
  
 
 0.762
ERG98069.1
Glutamate synthase domain 2.
     
 0.758
ERG98458.1
Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.
     
 0.733
ERG99294.1
Imidazoleglycerol-phosphate synthase; Belongs to the HisA/HisF family.
  
 
 0.698
Your Current Organism:
Haloquadratum sp. J07HQX50
NCBI taxonomy Id: 1238426
Other names: H. sp. J07HQX50
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.