STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERG98505.1Excinuclease ABC, A subunit. (982 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 
 0.999
ERH00019.1
GIY-YIG catalytic domain protein.
 
 0.971
ERH00020.1
Excinuclease ABC subunit C.
 
 0.969
ERG98558.1
Transglutaminase-like enzyme, putative cysteine protease.
    
  0.737
ERG99371.1
Exodeoxyribonuclease VII, large subunit.
 
   
 0.641
ERG97798.1
ATP-dependent exoDNAse (exonuclease V) beta subunit.
 
 
 0.637
ERG99739.1
Superfamily I DNA and RNA helicase.
 
 
 0.636
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
 
 0.602
ERG99140.1
ATP-dependent exoDNAse (exonuclease V) beta subunit.
 
 
 0.592
ERG98799.1
dephospho-CoA kinase.
 
  
 0.584
Your Current Organism:
Haloquadratum sp. J07HQX50
NCBI taxonomy Id: 1238426
Other names: H. sp. J07HQX50
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.