STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERG98597.1RecA/RadA recombinase. (63 aa)    
Predicted Functional Partners:
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
  
 0.808
pcn
PCNA-like DNA polymerase sliding clamp subunit protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
 
 0.787
ERG99261.1
Replication factor A.
 
 0.737
ERG97627.1
Superfamily II DNA/RNA helicase, SNF2 family.
   
 
 0.737
mptD
Uncharacterized protein conserved in archaea; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
  
     0.709
ERG99660.1
DNA mismatch repair enzyme (putative ATPase).
   
 
 0.706
ERG99661.1
DNA mismatch repair enzyme (putative ATPase).
   
 
 0.706
ERG98983.1
DNA repair exonuclease.
  
 0.675
ERG99337.1
NADH:ubiquinone oxidoreductase 49 kD subunit 7.
  
  
 0.662
ERG98684.1
Hypothetical protein.
 
 0.660
Your Current Organism:
Haloquadratum sp. J07HQX50
NCBI taxonomy Id: 1238426
Other names: H. sp. J07HQX50
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.