STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EME70422.1Methylated DNA-protein cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (154 aa)    
Predicted Functional Partners:
EME70421.1
COG1331 Highly conserved protein containing a thioredoxin domain.
       0.840
EME70423.1
COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.
  
    0.840
EME71807.1
COG2818 3-methyladenine DNA glycosylase.
   
 0.761
mnmE
GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
     0.726
EME70415.1
COG1192 ATPases involved in chromosome partitioning.
 
    0.680
EME70420.1
Hypothetical protein.
       0.674
EME70419.1
COG3411 Ferredoxin.
       0.673
rpoH
RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
  
 
 0.647
rpoH-2
RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
  
 
 0.647
EME68761.1
COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Belongs to the sigma-70 factor family.
  
 
 0.647
Your Current Organism:
Magnetospirillum caucaseum
NCBI taxonomy Id: 1244869
Other names: DSM 28995, M. caucaseum, Magnetospirillum caucaseum Dziuba et al. 2016, Magnetospirillum sp. SO-1, VKM B-2936, strain SO-1
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