| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EME70127.1 | EME70192.1 | H261_09989 | H261_09667 | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.948 |
| EME70127.1 | EME70566.1 | H261_09989 | H261_07363 | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Glutamate synthase [NADPH] large chain precursor; COG0067 Glutamate synthase domain 1. | 0.450 |
| EME70127.1 | EME71161.1 | H261_09989 | H261_04465 | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.969 |
| EME70127.1 | EME71294.1 | H261_09989 | H261_03828 | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | COG0067 Glutamate synthase domain 1. | 0.450 |
| EME70127.1 | EME71937.1 | H261_09989 | H261_00120 | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | COG0007 Uroporphyrinogen-III methylase. | 0.968 |
| EME70127.1 | hemC | H261_09989 | H261_09662 | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.989 |
| EME70127.1 | hemE | H261_09989 | H261_08098 | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.942 |
| EME70192.1 | EME70127.1 | H261_09667 | H261_09989 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.948 |
| EME70192.1 | EME71161.1 | H261_09667 | H261_04465 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.948 |
| EME70192.1 | EME71937.1 | H261_09667 | H261_00120 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | COG0007 Uroporphyrinogen-III methylase. | 0.948 |
| EME70192.1 | hemC | H261_09667 | H261_09662 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| EME70192.1 | hemE | H261_09667 | H261_08098 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.951 |
| EME70192.1 | hemH | H261_09667 | H261_08093 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.599 |
| EME70426.1 | EME71436.1 | H261_08088 | H261_03468 | COG1981 Predicted membrane protein. | COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.954 |
| EME70426.1 | hemE | H261_08088 | H261_08098 | COG1981 Predicted membrane protein. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.906 |
| EME70426.1 | hemH | H261_08088 | H261_08093 | COG1981 Predicted membrane protein. | Protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.992 |
| EME70566.1 | EME70127.1 | H261_07363 | H261_09989 | Glutamate synthase [NADPH] large chain precursor; COG0067 Glutamate synthase domain 1. | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.450 |
| EME70566.1 | EME71161.1 | H261_07363 | H261_04465 | Glutamate synthase [NADPH] large chain precursor; COG0067 Glutamate synthase domain 1. | COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.450 |
| EME70566.1 | EME71294.1 | H261_07363 | H261_03828 | Glutamate synthase [NADPH] large chain precursor; COG0067 Glutamate synthase domain 1. | COG0067 Glutamate synthase domain 1. | 0.999 |
| EME70566.1 | EME71436.1 | H261_07363 | H261_03468 | Glutamate synthase [NADPH] large chain precursor; COG0067 Glutamate synthase domain 1. | COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.447 |