STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
lysNAspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.905
glnA
Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.903
hprA
Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.902
pdhD_1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
ldhD_1
Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
    0.757
glnQ
Similar to ATP-binding component of ABC transporters; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.736
yajR
MFS transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.736
tcyM
Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.664
tcyN_2
Amino acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.664
tcyK
Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.642
Your Current Organism:
Leuconostoc mesenteroides
NCBI taxonomy Id: 1245
Other names: ATCC 8293, Ascococcus mesenteroides, Betacoccus arabinosaceus, CCUG 30066, CIP 102305, DSM 20343, HAMBI 2347, JCM 6124, L. mesenteroides, LMG 6893, LMG:6893, Leuconostoc sp. 13HN, NBRC 100496, NCDO 523, NCTC 12954, NRRL B-3470, strain 12954
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