| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apt | guaA | ARA02_06700 | ARA02_03120 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.981 |
| apt | pyrG | ARA02_06700 | ARA02_02490 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.406 |
| apt | xpt | ARA02_06700 | ARA02_09270 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.930 |
| argS | guaA | ARA02_05310 | ARA02_03120 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.978 |
| argS | lysS | ARA02_05310 | ARA02_01935 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.831 |
| argS | pyrG | ARA02_05310 | ARA02_02490 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.786 |
| argS | rplA | ARA02_05310 | ARA02_01250 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.556 |
| argS | tuf | ARA02_05310 | ARA02_03025 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.433 |
| guaA | apt | ARA02_03120 | ARA02_06700 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.981 |
| guaA | argS | ARA02_03120 | ARA02_05310 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.978 |
| guaA | guaB_1 | ARA02_03120 | ARA02_03110 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.999 |
| guaA | guaB_2 | ARA02_03120 | ARA02_03115 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| guaA | lysS | ARA02_03120 | ARA02_01935 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.984 |
| guaA | pyrG | ARA02_03120 | ARA02_02490 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.988 |
| guaA | rplA | ARA02_03120 | ARA02_01250 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.978 |
| guaA | tuf | ARA02_03120 | ARA02_03025 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.984 |
| guaA | upp | ARA02_03120 | ARA02_06530 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.981 |
| guaA | xpt | ARA02_03120 | ARA02_09270 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.981 |
| guaB_1 | guaA | ARA02_03110 | ARA02_03120 | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB_1 | guaB_2 | ARA02_03110 | ARA02_03115 | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | IMP dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.971 |