STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APE76732.1Type IV secretion system protein VirB4; Derived by automated computational analysis using gene prediction method: Protein Homology. (651 aa)    
Predicted Functional Partners:
APE76725.1
Type IV secretion system protein VirD4; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.869
lytM
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.814
APE76731.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.800
APE76730.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
APE76733.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
APE76735.1
Thiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.747
APE76736.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.746
APE76737.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.746
APE76722.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.740
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.517
Your Current Organism:
Leuconostoc mesenteroides
NCBI taxonomy Id: 1245
Other names: ATCC 8293, Ascococcus mesenteroides, Betacoccus arabinosaceus, CCUG 30066, CIP 102305, DSM 20343, HAMBI 2347, JCM 6124, L. mesenteroides, LMG 6893, LMG:6893, Leuconostoc sp. 13HN, NBRC 100496, NCDO 523, NCTC 12954, NRRL B-3470, strain 12954
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