STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APE76744.1Sortase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)    
Predicted Functional Partners:
APE76743.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.757
APE76742.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.716
APE76313.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.700
APE77307.1
Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.633
asa1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
 0.629
APE76369.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.554
APE76741.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S51 family.
 
     0.523
APE77381.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.486
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.444
dltB
D-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
  
   
 0.427
Your Current Organism:
Leuconostoc mesenteroides
NCBI taxonomy Id: 1245
Other names: ATCC 8293, Ascococcus mesenteroides, Betacoccus arabinosaceus, CCUG 30066, CIP 102305, DSM 20343, HAMBI 2347, JCM 6124, L. mesenteroides, LMG 6893, LMG:6893, Leuconostoc sp. 13HN, NBRC 100496, NCDO 523, NCTC 12954, NRRL B-3470, strain 12954
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